The 2019 winners edged closer to retaining their title after defeating Banbury United FC in Round 2. They will await Tividale FC or Premier League outfit Wolverhampton Wanderers, who are due to face each other on Wednesday 18 December.
After an impressive 2-0 victory against West Bromwich Albion, Romulus FC will face either Lye Town FC or Rushall Olympic FC away from home in the quarter-final. Meanwhile, after a dramatic penalty shootout victory, Tamworth FC will host Solihull Moors FC at The Lamb Ground.
A repeat of the 2018 Senior Challenge Cup Final is also a possibility with Nuneaton Borough FC progressing in the competition. They will face either Halesowen Town FC or Burton Albion FC at home.
All quarter-final ties are to be played on or before Saturday 25 January 2020.
Birmingham Senior Challenge Cup Quarter-Final Draw
Leamington FC vs. Tividale FC or Wolverhampton Wanderers
Lye Town FC or Rushall Olympic FC vs. Romulus FC
Tamworth FC vs. Solihull Moors FC
Nuneaton Borough FC vs. Halesowen Town FC or Burton Albion FC